By Mallinckrodt, CraigBy Molenberghs, GeertBy Lipkovich, IlyaBy Ratitch, Bohdana
The concepts of estimands, analyses (estimators) and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these topics. This book acts a practical guide to developing and implementing statistical analysis plans by explaining fundamental concept...s using accessible language; providing technical details; providing real world examples and providing SAS and R code to implement analyses.Read more
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Geert Molenberghs is Professor of Biostatistics (Hasselt University, KULeuven. He works on surrogate endpoints, longitudinal and incomplete data, was Editor for Applied Statistics, Biometrics, Biostatistics, Wiley Probability & Statistics, and Wiley StatsRef and is Executive Editor of Biometrics. He was President of the International Biometric Society, is Fellow of the American Statistical Association, and received the Guy Medal in Bronze from the Royal Statistical Society. He has held visiting positions at the Harvard School of Public Health. Ilya Lipkovich is a Sr. Research Advisor at Eli Lilly and Company. He is a Fellow of the American Statistical Association and published on subgroup identification in clinical data, analysis with missing data, and causal inference. He is a frequent presenter at conferences, a co-developer of subgroup identification methods, and a co-author of the book Analyzing Longitudinal Clinical Trial Data. A Practical Guide. Bohdana Ratitch is a Principal Research Scientist at Eli Lilly and Company. Bohdana has contributed to research and practical applications of methodologies for causal inference and missing data in clinical trials through active participation in a pharma industry working group, numerous publications, presentations, and co-authoring the book Clinical Trials with Missing Data: A Guide for Practitioners . Craig Mallinckrodt holds the rank of Distinguished Biostatistician at Biogen in Cambridge MA. He has extensive experience in all phases of clinical research. His methodology research focuses on longitudinal and incomplete data. He is Fellow of the American Statistical Association, has led several industry working groups on missing and longitudinal data, and received the Royal Statistical Society's award for outstanding contribution to the pharmaceutical industry.
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